Beyond this recommendation, however, some investigators have called for broader de-risking of patients with a CAC score of 0, suggesting that even those with familial hypercholesterolemia and a CAC score of 0 may not need add-on therapy beyond statins and ezetimibe. 7 The article by Mortensen et al 8 in this issue of JAMA Cardiology should give ... JAMA Cardiology is an international peer-reviewed journal and the definitive journal for clinical investigators, clinicians, and trainees in cardiovascular medicine …Key Points. Question Is there an association between normal systolic blood pressure values as currently defined and atherosclerotic cardiovascular disease among persons without traditional cardiovascular disease risk factors?. Findings In this cohort study including 1457 participants without atherosclerotic cardiovascular disease, beginning with a systolic …JAMA Cardiology Key Points Question What is the efficacy of evolocumab in patients with a low-density lipoprotein cholesterol level of 70 mg/dL or greater (or non–high-density lipoprotein cholesterol level of 100 mg/dL or greater) and recent (past 12 months) myocardial infarction (MI) treated with maximally tolerated high-intensity statin?Key Points. Question Does tafamidis, 80 mg, affect cardiac function in patients with transthyretin amyloid cardiomyopathy?. Findings In this post hoc analysis of the randomized Tafamidis in Transthyretin Cardiomyopathy Clinical Trial including 441 patients, over 30 months, there was less pronounced worsening of left ventricular (LV) stroke volume, LV …Additionally, information on cardiac arrest causative mechanism (presumed cardiac, respiratory, drug overdose, and other mechanism) and as to whether bystander cardiopulmonary resuscitation (CPR) or defibrillation …Improvement in cardiovascular outcomes has slowed, and the obesity epidemic that contributed to cardiovascular disease continues. Given the current uncertain state of knowledge, neither patients nor physicians can be confident that omega-3 fatty acids have any health benefits, yet in 2019 the global market for omega-3 fatty acids reached $4.1 ...Jul 1, 2020 · JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JAMA Cardiology, Chicago, Illinois. 57,031 likes · 154 talking about this · 9 were here. JAMA Cardiology is a member of the JAMA Network, a consortium of...Objective: To conduct a meta-analysis of all large trials assessing the associations of omega-3 fatty acid supplements with the risk of fatal and nonfatal …Jul 1, 2018 · Genetically elevated lipoprotein (a) and increased risk of myocardial infarction. JAMA. 2009;301 (22):2331-2339. PubMed Google Scholar. Clarke R, Peden JF, Hopewell JC, et al; PROCARDIS Consortium. Genetic variants associated with Lp (a) lipoprotein level and coronary disease. N Engl J Med. 2009;361 (26):2518-2528. Jul 1, 2020 · JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JAMA Cardiology. Key Points. Question Can coronary artery calcium score identify individuals likely to derive net benefit from aspirin therapy for primary prevention of atherosclerotic cardiovascular disease? Findings In this cohort study, using participants from the Dallas Heart Study cohort who were free from atherosclerotic cardiovascular ...In this issue of JAMA Cardiology, Felker et al 3 not only provide an important statement about the potential benefits and risks of omecamtiv mecarbil therapy but, more importantly, provide a clinically evident demarcation of a potentially new stage of HF, specifically patients with HFrEF who are receiving effective guideline-directed medical ...Disclaimer: Dr Thomas is the Assistant Editor for Statistics of JAMA Cardiology, Dr Hernandez is an Associate Editor for JAMA Cardiology, and Dr Fonarow is the Associate Editor of Health Care Quality and Guidelines for JAMA Cardiology, but they were not involved in any of the decisions regarding review of the manuscript or its acceptance.JAMA Cardiology. Home New Online Current Issue For Authors. Podcast. Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & …Key Points. Question Are accelerometer-measured physical activity (PA) and sedentary behavior associated with incident heart failure in older women?. Findings In this cohort study of 5951 women aged 63 to 99 years, usual daily light PA, moderate to vigorous PA, and steps per day were inversely associated, and total sedentary time positively …Key Points. Question Is myocardial inflammation present in patients recently recovered from COVID-19 and is this associated with tissue characterization abnormalities and blood biomarkers?. Findings In this cohort study of 47 participants recently recovered from COVID-19, myocardial inflammation was identified in a small proportion based on focal …Writing Committee Members, Otto CM , Nishimura RA , Bonow RO , et al. 2020 ACC/AHA guideline for the management of patients with valvular heart disease: executive summary: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.Key Points. Question How much would the highly atherogenic lipoprotein(a) have to be lowered to decrease the coronary heart disease outcomes in the same range as observed for a lowering of low-density lipoprotein cholesterol by 38.67 mg/dL?. Findings In this mendelian randomization analysis, it was estimated that lipoprotein(a) would have to …JAMA Cardiology. JAMA Guide to Statistics and Methods. Overlap Weighting—A Propensity Score Method That Mimics Attributes of a Randomized Clinical Trial. Laine E. Thomas, PhD; Fan Li, PhD; Michael J. Pencina, PhD. JAMA. Original Investigation. Association of ACEI or ARB Use With COVID-19 Diagnosis and Mortality.Explore the latest advances in PCI and device therapy, treatment of myocardial infarction, dyslipidemia, heart failure, afib & rhythm disorders, TAVR, …This analysis of data from the 2016 Global Burden of Disease Study examines the national and province-level mortality, prevalence, and disability-adjusted life-years associated with cardiovascular disease in China from 1990 to 2016.Key Points. Question Can a remote, algorithm-driven, navigator-administered medication optimization program enhance implementation of guideline-directed medical therapy in heart failure with reduced ejection fraction?. Findings In this case-control study of 1028 patients, in 3 months, patients participating in the remote intervention experienced significant …Key Points. Question Do contemporary machine learning methods improve prediction of in-hospital death after hospitalization for acute myocardial infarction (AMI)?. Findings In this cohort study of 755 402 patients with AMI in a nationwide registry, machine learning models that used the same data inputs as logistic regression were not associated with …JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary …Jul 1, 2020 · JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JAMA Cardiology. Medical News & Perspectives. Highlights From the American Heart Association’s Scientific Sessions—ApoB as a Risk Marker, an Oral PCSK9 Inhibitor, Aspirin and Dementia, and More. Jennifer Abbasi. …Key Points. Question Do contemporary machine learning methods improve prediction of in-hospital death after hospitalization for acute myocardial infarction (AMI)?. Findings In this cohort study of 755 402 patients with AMI in a nationwide registry, machine learning models that used the same data inputs as logistic regression were not associated with …Jan 14, 2021 · Thirty of 789 athletes (3.8%) had abnormal cardiac screening test results necessitating additional evaluation and downstream testing; 5 athletes (0.6%) were detected to have findings raising concern for COVID-19–associated inflammatory heart disease that resulted in restriction from sport participation per American Heart Association (AHA)/American College of Cardiology (ACC) guidelines. 10 ... Key Points. Question Are initial and serial increases in high-sensitivity C-reactive protein levels after acute coronary syndrome in medically optimized patients associated with increased risk of a major cardiac event, cardiovascular death, and all-cause death?. Findings In this secondary analysis of the VISTA-16 randomized clinical trial that …August 1, 2017. Treatment of Cholesterol in 2017. Harlan M. Krumholz, MD, SM 1,2. Author Affiliations Article Information. 1 Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine. 2 The Center for Outcomes Research and Evaluation, Yale–New Haven Health, New Haven, Connecticut. Das SR , Everett BM , Birtcher KK , et al. 2018 ACC expert consensus decision pathway on novel therapies for cardiovascular risk reduction in patients with type 2 diabetes and atherosclerotic cardiovascular disease: a report of the American College of Cardiology task force on expert consensus decision pathways. JAMA Cardiology. Key Points. Question What is the risk of aortic dissection (AD) and all-cause death for nonsyndromic patients with unrepaired ascending thoracic aortic aneurysm (TAA), overall and by … JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JAMA Cardiology Key Points Question What is the efficacy of evolocumab in patients with a low-density lipoprotein cholesterol level of 70 mg/dL or greater (or non–high-density lipoprotein cholesterol level of 100 mg/dL or greater) and recent (past 12 months) myocardial infarction (MI) treated with maximally tolerated high-intensity statin? JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Beyond this recommendation, however, some investigators have called for broader de-risking of patients with a CAC score of 0, suggesting that even those with familial hypercholesterolemia and a CAC score of 0 may not need add-on therapy beyond statins and ezetimibe. 7 The article by Mortensen et al 8 in this issue of JAMA Cardiology … Mehta LS , Beckie TM , DeVon HA , et al; American Heart Association Cardiovascular Disease in Women and Special Populations Committee of the Council on Clinical Cardiology, Council on Epidemiology and Prevention, Council on Cardiovascular and Stroke Nursing, and Council on Quality of Care and Outcomes Research. Training and credentialing guidelines are inconsistent across medical fields, with cardiology requiring 150 studies performed and 300 interpreted before independent practice 23 while the American College of Emergency Physicians allows as few as 25 cardiac studies for competence. 24 An unintended consequence of varying training …Beyond this recommendation, however, some investigators have called for broader de-risking of patients with a CAC score of 0, suggesting that even those with familial hypercholesterolemia and a CAC score of 0 may not need add-on therapy beyond statins and ezetimibe. 7 The article by Mortensen et al 8 in this issue of JAMA Cardiology …JAMA Cardiology. Home New Online Current Issue For Authors. Podcast. Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & …Key Points. Questions What is the 20-year prevalence of food insecurity among individuals with cardiovascular disease or cardiometabolic risk factors, and does this prevalence differ across racial and ethnic groups?. Findings In this cross-sectional study of noninstitutionalized US adults from 1999 through 2018, food insecurity increased over … Hindricks G , Potpara T , Dagres N , et al; ESC Scientific Document Group. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): the task force for the diagnosis and management of atrial fibrillation of the European Society of Cardiology (ESC) developed with the special ... JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Cardiology. Explore the latest in cardiology, including treatment of acute coronary syndromes, dyslipidemia, heart failure, rhythm disorders, and more. Add to My Interests. Douglas PS , Garcia MJ , Haines DE , et al; American College of Cardiology Foundation Appropriate Use Criteria Task Force; American Society of Echocardiography; American Heart Association; American Society of Nuclear Cardiology; Heart Failure Society of America; Heart Rhythm Society; Society for Cardiovascular Angiography and Interventions; Society of Critical Care Medicine; Society of ... With the exception of the flu pandemic years of 1918-1920, heart disease (HD) has been the leading cause of death in the United States since 1910, 1 with cancer and stroke among the 5 leading causes of death every year since 1924. 2 From 2000 to 2010, age-adjusted mortality decreased 30% for HD and 36% for stroke, but cancer mortality … JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Given the evidence of the effectiveness of statins in reducing atherosclerotic cardiovascular disease (ASCVD) events and mortality, the 2013 American College of Cardiology (ACC) and the American Heart Association (AHA) cholesterol treatment guidelines recommended high-intensity statins for most patients with ASCVD. 1 The recently updated 2018 cholesterol …Key Points. Questions What is the 20-year prevalence of food insecurity among individuals with cardiovascular disease or cardiometabolic risk factors, and does this prevalence differ across racial and ethnic groups?. Findings In this cross-sectional study of noninstitutionalized US adults from 1999 through 2018, food insecurity increased over …Training and credentialing guidelines are inconsistent across medical fields, with cardiology requiring 150 studies performed and 300 interpreted before independent practice 23 while the American College of Emergency Physicians allows as few as 25 cardiac studies for competence. 24 An unintended consequence of varying training …Aug 1, 2022 · Piepoli MF , Hoes AW , Agewall S , et al; ESC Scientific Document Group. 2016 European guidelines on cardiovascular disease prevention in clinical practice: the Sixth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of 10 societies and by invited experts): developed with ... Training and credentialing guidelines are inconsistent across medical fields, with cardiology requiring 150 studies performed and 300 interpreted before independent practice 23 while the American College of Emergency Physicians allows as few as 25 cardiac studies for competence. 24 An unintended consequence of varying training …JAMA Cardiology. Key Points. Question How many clinically significant variants for familial hypercholesterolemia would be missed by limited-variant screening conducted on microarrays? Findings In this cross-sectional review of comprehensive genetic test results for individuals with indications for familial hypercholesterolemia, a limited ...JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary …Improvement in cardiovascular outcomes has slowed, and the obesity epidemic that contributed to cardiovascular disease continues. Given the current uncertain state of knowledge, neither patients nor physicians can be confident that omega-3 fatty acids have any health benefits, yet in 2019 the global market for omega-3 fatty acids reached $4.1 ...JAMA Cardiology. Key Points. Question What is the association of body mass index with cardiovascular disease (CVD) morbidity and mortality? Findings In this population-based study, overweight and obesity were associated with … JAMA Cardiology ’s impact factor was 30.2 in 2022 (which is reported for 2021). The journal’s weekly online content is now delivered to more than 97 000 readers, with 3.3 million annual article views and downloads. We maintain an active presence on social media, with an increase during the past year to more than 114 000 Twitter and Facebook ... JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med. 2001;345 (20):1435-1443. PubMed Google Scholar Crossref. Miller LW, Pagani FD, Russell SD, et al; HeartMate II Clinical Investigators. Use of a continuous-flow device in …JAMA Cardiology. Home New Online Current Issue For Authors. Podcast. Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA …Key Points. Question What are the efficacy and safety of omecamtiv mecarbil for the treatment of patients with severe heart failure (HF)?. Finding In this post hoc analysis of data from 8232 patients with symptomatic HF enrolled in the Global Approach to Lowering Adverse Cardiac Outcomes Through Improving Contractility in Heart Failure …Key Points. Question In statin-treated patients at high cardiovascular risk with elevated triglyceride levels and low levels of high-density lipoprotein cholesterol treated with ω-3 fatty acids, are achieved levels of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) associated with cardiovascular outcomes?. Findings In a secondary analysis of a … The daily doses of EPA varied from 226 to 1800 mg/day, and DHA varied from 0 to 1700 mg/day. The mean duration of treatment in individual trials varied from 1.0 year to 6.2 years (weighted mean, 4.4 years). Of the 77 917 participants, 47 803 (61.4%) were men, and the mean age at entry was 64 years. Key Points. Question Can a deep learning model using routinely acquired outpatient 12-lead electrocardiograms (ECGs) in sinus rhythm predict the presence of atrial fibrillation (AF) within 31 days across diverse populations?. Findings In this prognostic study, a model trained on data from 2 large Veterans Affairs (VA) hospital networks predicted AF with …Additionally, information on cardiac arrest causative mechanism (presumed cardiac, respiratory, drug overdose, and other mechanism) and as to whether bystander cardiopulmonary resuscitation (CPR) or defibrillation …Key Points. Question In statin-treated patients at high cardiovascular risk with elevated triglyceride levels and low levels of high-density lipoprotein cholesterol treated with ω-3 fatty acids, are achieved levels of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) associated with cardiovascular outcomes?. Findings In a secondary analysis of a … JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Key Points. Question In patients diagnosed with atrial fibrillation before 66 years of age, what is the prevalence of disease-associated variants in susceptibility genes for inherited cardiomyopathy and arrhythmia syndromes?. Findings In this cohort study, among 1293 participants who underwent whole genome sequencing, disease-associated rare …Key Points. Question Can mendelian randomization identify associations between circulating cardiovascular disease–related proteins and hypertensive disorders of pregnancy (HDPs)?. Findings In this genetic association study including data from 21 758 participants for cardiovascular disease–related proteins, 393 238 female individuals for gestational …Importance Limited evidence suggests exercise reduces blood pressure (BP) in individuals with resistant hypertension, a clinical population with low responsiveness to drug therapy.. Objective To determine whether an aerobic exercise training intervention reduces ambulatory BP among patients with resistant hypertension.. Design, Settings, and …Given the evidence of the effectiveness of statins in reducing atherosclerotic cardiovascular disease (ASCVD) events and mortality, the 2013 American College of Cardiology (ACC) and the American Heart Association (AHA) cholesterol treatment guidelines recommended high-intensity statins for most patients with ASCVD. 1 The recently updated 2018 cholesterol …Our acceptance rate of 7% for original science manuscripts is on par with the other major journals in our field. After only 3 years of publishing, JAMA Cardiology’s impact factor was 11.9 in 2019 (which is reported for 2018). As anticipated, the continuous flow of manuscripts has increased the workload of our very busy editors, but we relish ...Key Points. Question How much would the highly atherogenic lipoprotein(a) have to be lowered to decrease the coronary heart disease outcomes in the same range as observed for a lowering of low-density lipoprotein cholesterol by 38.67 mg/dL?. Findings In this mendelian randomization analysis, it was estimated that lipoprotein(a) would have to …Improvement in cardiovascular outcomes has slowed, and the obesity epidemic that contributed to cardiovascular disease continues. Given the current uncertain state of knowledge, neither patients nor physicians can be confident that omega-3 fatty acids have any health benefits, yet in 2019 the global market for omega-3 fatty acids reached $4.1 ...Key Points. Question Do contemporary machine learning methods improve prediction of in-hospital death after hospitalization for acute myocardial infarction (AMI)?. Findings In this cohort study of 755 402 patients with AMI in a nationwide registry, machine learning models that used the same data inputs as logistic regression were not associated with …McMurray JJ , Adamopoulos S , Anker SD , et al; ESC Committee for Practice Guidelines. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology developed in collaboration with the Heart Failure Association (HFA) of … JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Heidenreich PA , Bozkurt B , Aguilar D , et al. 2022 AHA/ACC/HFSA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Key Points. Question Is myocardial inflammation present in patients recently recovered from COVID-19 and is this associated with tissue characterization abnormalities and blood biomarkers?. Findings In this cohort study of 47 participants recently recovered from COVID-19, myocardial inflammation was identified in a small proportion based on focal …Key Points. Question Is patient sex associated with differences in clinical outcomes of pulsed field ablation (PFA) for the treatment of patients with atrial fibrillation (AF)?. Findings In this large cohort study using a patient-level registry including 1568 consecutive patients who underwent PFA for paroxysmal or persistent AF, there was no significant difference … Douglas PS , Garcia MJ , Haines DE , et al; American College of Cardiology Foundation Appropriate Use Criteria Task Force; American Society of Echocardiography; American Heart Association; American Society of Nuclear Cardiology; Heart Failure Society of America; Heart Rhythm Society; Society for Cardiovascular Angiography and Interventions; Society of Critical Care Medicine; Society of ... Disclaimer: Dr O’Donnell is an associate editor of JAMA Cardiology, but he was not involved in any of the decisions regarding review of the manuscript or its acceptance. References 1. Greene SJ , Butler J , Albert NM , et al. Medical therapy for heart failure with reduced ejection fraction: the CHAMP-HF Registry. ...Key Points. Question What are the trends in characteristics and outcomes of adult heart transplant after implementation of the new heart allocation policy on October 18, 2018?. Findings In this cohort study of 15 631 patients, with the heart allocation policy change, higher-risk recipients are now undergoing transplant, with higher rates of bridging with …JAMA Cardiology. Home New Online Current Issue For Authors. Podcast. Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA …Jul 1, 2022 · Corresponding Author: Arshed A. Quyyumi, MD, Division of Cardiology, Department of Medicine, Emory University School of Medicine, 1462 Clifton Rd NE, Ste 507, Atlanta, GA 30322 ([email protected]). Author Contributions : Dr Quyyumi had full access to all of the data in the study and takes responsibility for the integrity of the data and the ... JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) We would like to show you a description here but the site won’t allow us.Introduction. In rural and regional settings, reperfusion therapy for ST-segment elevation myocardial infarction (STEMI) involves thrombolysis followed by transfer to a percutaneous coronary intervention (PCI)–capable hospital. 1, 2 Rapid and correct diagnosis is the first step in the chain of survival for patients with STEMI.JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary …Mn gophers volleyball, Anthony's brick oven pizza, Mercer island thrift store, Hardee's breakfast times, Matlock obgyn, Noemis, Caverns tn, Aireco supply, Indiana motorbike, Rural king effingham illinois, City of anadarko, City of johnstown, Books2door, Maui built
JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary …. Aplaceinthesun
JAMA Cardiology is an international peer-reviewed journal and the definitive journal for clinical investigators, clinicians, and trainees in cardiovascular medicine …Key Points. Question Is patient sex associated with differences in clinical outcomes of pulsed field ablation (PFA) for the treatment of patients with atrial fibrillation (AF)?. Findings In this large cohort study using a patient-level registry including 1568 consecutive patients who underwent PFA for paroxysmal or persistent AF, there was no significant difference …A, Probability of the primary composite end point, with extrapolated mean event-free survival time at age 65 years of 6.2 years for placebo and 8.3 years for dapagliflozin (difference, 2.1 years; 95% CI, 0.8-3.3 years; P = .002).B, Probability of death from any cause, with mean extrapolated life expectancy of 9.1 years for placebo and 10.8 years for dapagliflozin (difference, 1.7 years; 95% …The 2018 American College of Cardiology (ACC)/American Heart Association (AHA)/Heart Rhythm Society (HRS) Guideline on the Evaluation and Management of Patients with Bradycardia and Cardiac Conduction Delay offers guidance to clinicians for the treatment of adult patients with bradycardia or symptoms thought to be associated with bradycardia or cardiac conduction …Piepoli MF , Hoes AW , Agewall S , et al; ESC Scientific Document Group. 2016 European guidelines on cardiovascular disease prevention in clinical practice: the Sixth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of …JAMA Cardiology. Rare cases of cardiac inflammation following SARS-CoV-2 vaccination have been reported. 1-4 We reviewed the clinical records of vaccine recipients to identify cases of postvaccination myocarditis or pericarditis. Methods Forty hospitals in Washington, Oregon, Montana, and Los Angeles County, California, that …JAMA Cardiology. Home New Online Current Issue For Authors. Podcast. Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA …10.1001/jamacardio.2018.0022. . Abstract. . Importance: Prior studies have demonstrated lower all-cause mortality in individuals who are overweight … JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Key Points. Question What are the trends in heart failure (HF)–related mortality in young adults?. Findings In this cohort study, 61 729 HF-related deaths were identified in young adults between 1999 and 2019, and the overall age-adjusted mortality rate per 100 000 persons increased from 2.36 in 1999 to 3.16 in 2019. 10.1001/jamacardio.2018.0022. . Abstract. . Importance: Prior studies have demonstrated lower all-cause mortality in individuals who are overweight … JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JAMA Cardiology. In our annual review of JAMA Cardiology, I am pleased to report that 2022 marked another year of steady growth in publishing original …JAMA Cardiology. Full Text. Leaving the broken system the way it is, that’s not a solution. 1. Barack Obama. It must be recognized that our current health care delivery system has failed to adequately treat 2 of our nation’s top cardiovascular risk factors: high blood pressure (BP) and hyperlipidemia.JAMA Cardiology Key Points Question What is the efficacy of evolocumab in patients with a low-density lipoprotein cholesterol level of 70 mg/dL or greater (or non–high-density lipoprotein cholesterol level of 100 mg/dL or greater) and recent (past 12 months) myocardial infarction (MI) treated with maximally tolerated high-intensity statin? This cross-sectional study examines data from the National Health and Nutrition Examination Survey to assess the prevalence of food insecurity among individuals with cardiovascular disease or cardiometabolic risk factors and analyze any differences across racial and ethnic groups. JAMA Cardiology. Coronavirus disease 2019 (COVID-19) is associated with significant mortality and morbidity, including adverse cardiovascular sequelae. 1 As public health policy begins to guide the resumption of recreational and competitive sport, clinicians are charged with determining when competitive athletes and highly active individuals ...Shown are the means for the estimated glomerular filtration rate (eGFR) over a period of 36 months. The whiskers indicate 95% CIs. The eGFR was calculated according to the creatinine formula developed by the Chronic Kidney Disease Epidemiology Collaboration study. 19 Effect estimates are based on a mixed-model repeated-measures analysis in patients who had a …A, Overall survival of patients with DNMT3A or TET2 mutations with a VAF greater than 0.005 to 0.01; a VAF of at least 0.01 to 0.02; a VAF of at least 0.02; and non-CHIP patients reveals dose-response of clone size and clinical outcome; B, Event-free survival free of death or rehospitalization for heart failure with DNMT3A or TET2 mutations at various …McMurray JJ , Adamopoulos S , Anker SD , et al; ESC Committee for Practice Guidelines. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology developed in collaboration with the Heart Failure Association (HFA) of …Shown are the means for the estimated glomerular filtration rate (eGFR) over a period of 36 months. The whiskers indicate 95% CIs. The eGFR was calculated according to the creatinine formula developed by the Chronic Kidney Disease Epidemiology Collaboration study. 19 Effect estimates are based on a mixed-model repeated-measures analysis in patients who had a … The daily doses of EPA varied from 226 to 1800 mg/day, and DHA varied from 0 to 1700 mg/day. The mean duration of treatment in individual trials varied from 1.0 year to 6.2 years (weighted mean, 4.4 years). Of the 77 917 participants, 47 803 (61.4%) were men, and the mean age at entry was 64 years. Jan 1, 2021 · Myocarditis is a significant cause of sudden cardiac death in competitive athletes and can occur with normal ventricular function. 1 Recent studies have raised concerns of myocardial inflammation after recovery from coronavirus disease 2019 (COVID-19), even in asymptomatic or mildly symptomatic patients. 2 Our objective was to investigate the use of cardiac magnetic resonance (CMR) imaging in ... JAMA Cardiology. Key Points. Question Can coronary artery calcium score identify individuals likely to derive net benefit from aspirin therapy for primary prevention of atherosclerotic cardiovascular disease? Findings In this cohort study, using participants from the Dallas Heart Study cohort who were free from atherosclerotic cardiovascular ...Disclaimer: Dr O’Donnell is an associate editor of JAMA Cardiology, but he was not involved in any of the decisions regarding review of the manuscript or its acceptance. References 1. Greene SJ , Butler J , Albert NM , et al. Medical therapy for heart failure with reduced ejection fraction: the CHAMP-HF Registry. ...JAMA Cardiology. JAMA Guide to Statistics and Methods. Overlap Weighting—A Propensity Score Method That Mimics Attributes of a Randomized Clinical Trial. Laine E. Thomas, PhD; Fan Li, PhD; Michael J. Pencina, PhD. JAMA. Original Investigation. Association of ACEI or ARB Use With COVID-19 Diagnosis and Mortality.JAMA Cardiology. Key Points. Question What is the risk of aortic dissection (AD) and all-cause death for nonsyndromic patients with unrepaired ascending thoracic aortic aneurysm (TAA), overall and by … This secondary analysis of a randomized clinical trial investigates the association between plasma levels of eicosapentaenoic acid and docosahexaenoic acid and cardiovascular outcomes in a trial of ω-3 fatty acids compared with corn oil placebo. Key Points. Question What is the temporal association between episodes of atrial fibrillation (AF) and ischemic stroke in patients with cardiac implantable electronic devices (CIEDs)?. Findings In this case-crossover study including 891 patients with CIEDs and ischemic stroke, multihour AF episodes raised the odds of stroke 3.7-fold for up to 30 days.Aug 1, 2022 · Piepoli MF , Hoes AW , Agewall S , et al; ESC Scientific Document Group. 2016 European guidelines on cardiovascular disease prevention in clinical practice: the Sixth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of 10 societies and by invited experts): developed with ... JAMA Cardiology. Key Points. Question Can coronary artery calcium score identify individuals likely to derive net benefit from aspirin therapy for primary prevention of atherosclerotic cardiovascular disease? Findings In this cohort study, using participants from the Dallas Heart Study cohort who were free from atherosclerotic cardiovascular ...JAMA Cardiology is a peer-reviewed journal that publishes original research, reviews, and opinions on cardiovascular medicine. Browse the latest news … JAMA Cardiology ’s impact factor was 30.2 in 2022 (which is reported for 2021). The journal’s weekly online content is now delivered to more than 97 000 readers, with 3.3 million annual article views and downloads. We maintain an active presence on social media, with an increase during the past year to more than 114 000 Twitter and Facebook ... JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts …JAMA Cardiology. Key Points. Question Can coronary artery calcium score identify individuals likely to derive net benefit from aspirin therapy for primary prevention of atherosclerotic cardiovascular disease? Findings In this cohort study, using participants from the Dallas Heart Study cohort who were free from atherosclerotic cardiovascular ... JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Shown are the means for the estimated glomerular filtration rate (eGFR) over a period of 36 months. The whiskers indicate 95% CIs. The eGFR was calculated according to the creatinine formula developed by the Chronic Kidney Disease Epidemiology Collaboration study. 19 Effect estimates are based on a mixed-model repeated-measures analysis in patients who had a …JAMA Cardiology. Key Points. Question How is kidney transplant associated with cardiovascular functional reserve? Findings In this cohort study of 166 patients with stage 5 chronic kidney disease and 87 patients with hypertension only to assess change to cardiovascular functional reserve after improving the uremic milieu through a kidney ...Key Points. Question In patients diagnosed with atrial fibrillation before 66 years of age, what is the prevalence of disease-associated variants in susceptibility genes for inherited cardiomyopathy and arrhythmia syndromes?. Findings In this cohort study, among 1293 participants who underwent whole genome sequencing, disease-associated rare …Key Points. Question What are the efficacy and safety of omecamtiv mecarbil for the treatment of patients with severe heart failure (HF)?. Finding In this post hoc analysis of data from 8232 patients with symptomatic HF enrolled in the Global Approach to Lowering Adverse Cardiac Outcomes Through Improving Contractility in Heart Failure …Key Points. Question What is the diagnostic and prognostic value of stress cardiovascular magnetic resonance imaging (CMR) for the evaluation of stable chest pain?. Findings In this systematic review and meta-analysis pooling 74 470 patients with stable chest pain over 381 357 person-years of follow-up, stress CMR yielded high diagnostic accuracy and …JAMA Cardiology. Home New Online Current Issue For Authors. Podcast. Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA …Two articles published in JAMA Cardiology from 2 academic hospitals in Wuhan, China, the epicenter of the COVID-19 pandemic, 10,11 support these concepts while also providing novel insights into the incidence and consequences of myocardial injury associated with SARS-CoV-2.JAMA Cardiology. Home New Online Current Issue For Authors. Podcast. Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA …Importance Primary prevention of atherosclerotic cardiovascular disease (ASCVD) relies on risk stratification. Genome-wide polygenic risk scores (PRSs) are proposed to improve ASCVD risk estimation. Objective To determine whether genome-wide PRSs for coronary artery disease (CAD) and acute ischemic stroke improve ASCVD risk estimation with traditional clinical risk …Importance Limited evidence suggests exercise reduces blood pressure (BP) in individuals with resistant hypertension, a clinical population with low responsiveness to drug therapy.. Objective To determine whether an aerobic exercise training intervention reduces ambulatory BP among patients with resistant hypertension.. Design, Settings, and …Jul 1, 2018 · Genetically elevated lipoprotein (a) and increased risk of myocardial infarction. JAMA. 2009;301 (22):2331-2339. PubMed Google Scholar. Clarke R, Peden JF, Hopewell JC, et al; PROCARDIS Consortium. Genetic variants associated with Lp (a) lipoprotein level and coronary disease. N Engl J Med. 2009;361 (26):2518-2528. All the players in the study, which was published in JAMA Cardiology, had asymptomatic or nonsevere SARS-CoV-2 infections and were scanned 11 to 53 days after quarantining for 2 weeks. Cardiac magnetic resonance imaging shows pericardial effusion (indicated by arrow) in an Ohio State University competitive athlete recovering from coronavirus ...With aging, telomerase knockout mice hearts showed shortening of telomeres, attenuated proliferation and increased apoptosis of cardiomyocytes, and greater cardiac remodeling and left ventricular failure. 30,31 On the other hand, enhanced expression of telomerase reverse transcriptase in rat cardiomyocytes preserved …Beneficial associations of low and large doses of leisure time physical activity with all-cause, cardiovascular disease and cancer mortality: a national cohort study of 88,140 US adults. Br J Sports Med. 2019;53 (22):1405-1411. doi: 10.1136/bjsports-2018 …Key Points. Question In statin-treated patients at high cardiovascular risk with elevated triglyceride levels and low levels of high-density lipoprotein cholesterol treated with ω-3 fatty acids, are achieved levels of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) associated with cardiovascular outcomes?. Findings In a secondary analysis of a …JAMA Cardiology. Editor's Comment. A Brief Window to Rethink Emergency Care. Melinda B. Buntin, PhD. JAMA Health Forum. We are in the midst of the coronavirus disease 2019 (COVID-19) pandemic and, as many clinicians across the globe, we are seeing firsthand the pain and death caused by COVID-19.This analysis of pooled data from 2 randomized clinical trials evaluates the 5-year incidence, clinical outcomes, and predictors of hemodynamic structural valve deterioration in patients undergoing self-expanding transcatheter aortic valve implantation or surgery.Importance Previous studies of basic cardiopulmonary resuscitation (CPR) indicate that both chest compression rate (CCR) and chest compression depth (CCD) each are associated with survival probability after out-of-hospital cardiac arrest. However, an optimal CCR-CCD combination has yet to be identified, particularly with respect to age, …Importance Cardiovascular disease is a leading cause of morbidity in cancer survivors, which makes strategies aimed at mitigating cardiovascular risk a subject of major contemporary importance.. Objective To assess whether a center-based cardiac rehabilitation (CBCR) framework compared with usual care encompassing community-based exercise training …JAMA Cardiology. Key Points. Question Does routine ultrasonography guidance for femoral arterial access for cardiac procedures reduce bleeding or vascular complications? Findings In this randomized clinical trial that included 621 patients, ...ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of ...The 2018 American College of Cardiology (ACC)/American Heart Association (AHA)/Heart Rhythm Society (HRS) Guideline on the Evaluation and Management of Patients with Bradycardia and Cardiac Conduction Delay offers guidance to clinicians for the treatment of adult patients with bradycardia or symptoms thought to be associated with bradycardia or cardiac conduction …Key Points. Question Is there an association between normal systolic blood pressure values as currently defined and atherosclerotic cardiovascular disease among persons without traditional cardiovascular disease risk factors?. Findings In this cohort study including 1457 participants without atherosclerotic cardiovascular disease, beginning with a systolic …JAMA Cardiology. Key Points. Question Can readily available electrocardiogram (ECG) data be used to train a high-performing convolutional neural network (CNN) across a large …JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959)ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of ...Mission Statement: JAMA Cardiology is positioned at the nexus of clinical investigation, actionable clinical science, and clinical practice, with emphasis on …JAMA Cardiology. Key Points. Question Is COVID-19 vaccination linked to the occurrence of myocarditis? Findings In this study of 7 patients with acute myocarditis, 4 occurred within 5 days of COVID-19 vaccination between February 1 and April 30, 2021. All 4 ...JAMA Cardiology. Home New Online Current Issue For Authors. Podcast. Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA …JAMA Network is a consortium of peer-reviewed medical publications that includes JAMA® and the JAMA Network journals. JAMA Cardiology does not hold itself responsible for statements made by any contributor. All articles published, including opinion articles, represent the views of the authors and do not reflect the policy of the Journal, the ...JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary …Key Points. Question What is the diagnostic and prognostic value of stress cardiovascular magnetic resonance imaging (CMR) for the evaluation of stable chest pain?. Findings In this systematic review and meta-analysis pooling 74 470 patients with stable chest pain over 381 357 person-years of follow-up, stress CMR yielded high diagnostic accuracy and …DOI: 10.1001/jamacardio.2021.3055. Abstract. Importance: The density of atherosclerotic plaque forms the basis for categorizing calcified and noncalcified …Smoothed conditional mean plots visualizing the variation of incidence rates of myocardial infarction with 95% CI by different weather parameters. Unadjusted and adjusted incidence rate ratio (IRR) and 95% CI from regression analyses are presented with each graph. Results from the regression analyses are interpreted as change per increase in ...Key Points. Question Are accelerometer-measured physical activity (PA) and sedentary behavior associated with incident heart failure in older women?. Findings In this cohort study of 5951 women aged 63 to 99 years, usual daily light PA, moderate to vigorous PA, and steps per day were inversely associated, and total sedentary time positively …JAMA Cardiology. Home New Online Current Issue For Authors. Podcast. Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & … Beyond this recommendation, however, some investigators have called for broader de-risking of patients with a CAC score of 0, suggesting that even those with familial hypercholesterolemia and a CAC score of 0 may not need add-on therapy beyond statins and ezetimibe. 7 The article by Mortensen et al 8 in this issue of JAMA Cardiology should give ... Disclaimer: Dr Hernandez is Associate Editor of JAMA Cardiology, but he was not involved in any of the decisions regarding review of the manuscript or its acceptance. Meeting Presentation: This paper was presented at the Heart Failure Society of America Annual Scientific Meeting 2022; October 3, 2022; Washington, DC.. 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